CUSTOM SYNTHESIS & LIBRARY

Complex Chemistry. Made Tangible.

From individual custom peptides to structurally diverse libraries, we deliver high-quality peptide material with speed, precision and reproducibility.

Discuss Your Molecule
CUSTOM PEPTIDE SYNTHESIS

Capability That Flexes With Your Program.

Our capabilities span modern peptide chemistry, from simple linear sequences to highly modified and structurally complex therapeutic candidates.

Scale:Milligram → Gram → Multi-Gram
Applications:Feasibility · Lead Optimization · Pre-clinical · IND-enabling Studies
01

Fmoc SPPS

02

Solution-Phase Synthesis

03

Hybrid Solid/Solution Phase

Peptide Synthesis Reaction Workflow and Molecular Assembly
Integrated Peptide Synthesis Hub
04

Chemical Protein Synthesis

05

Cyclization

06

Conjugation & Labelling

STRUCTURAL & CHEMICAL MODIFICATIONS

Built-In Flexibility for Optimizing Candidates.

A broad range of structural, amino acid and conjugation chemistry supports peptide candidate optimization.

Modified Peptide Backbone and Unnatural Amino Acid Structures
01

Amino Acid & Backbone

  • D-amino acids
  • N-methylation
  • Beta & gamma amino acids
  • Alpha-methyl amino acids
  • Unnatural amino acids
  • Pseudoprolines
Peptide Connected to Functional Bioconjugation Groups
02

Conjugation & Labelling

  • PEGylation
  • Fatty acid conjugation
  • Fluorescent labelling
  • Biotin conjugation
  • Click chemistry
  • Phosphorylation
  • Glycosylation
  • Isotopic labelling
Circular Macrocyclic Peptide Molecular Structure
03

Cyclization Strategies

  • Head-to-tail
  • Lactam bridge
  • Disulfide bond
  • Hydrocarbon stapling
  • Thioether / triazole
  • Bicyclization
Explore Cyclization & Macrocyclic Design
Syro II Multi-Channel Parallel Automated Synthesizer
LIBRARY SYNTHESIS

More Molecules. More Learning.

The Syro II parallel synthesizer enables rapid generation of structurally diverse peptide collections for screening, SAR studies and hit-to-lead optimization.

Parallel Production

Multiple unique peptide sequences synthesized simultaneously with 48 channels of current capacity.

Design Flexibility

Focused, scanning, truncation, substitution, cyclic, macrocyclic and other specialized peptide libraries.

Analytical Support

UPLC-UV and UPLC-MS for identity confirmation and crude purity assessment.

Conjugate Options

Natural and unnatural amino acids, modifications, conjugates and macrocyclic scaffolds.

POWERED BY SYRO II

Automated. Precise. Reproducible.

A technical presentation of our premier multi-channel parallel robotic platform for unattended synthesis.

Syro II High Precision Robotic Automated Synthesizer
01Automated Fmoc SPPS
02Precise Reagent Delivery
03Flexible Scale
04Controlled Wash Cycles
05High Reproducibility
END-TO-END WORKFLOW

Library Design → Synthesis → Analysis

A seamless continuous workflow connecting initial library strategy to actionable SAR screening data.

01

Design

Library strategy & peptide sequences

02

Synthesize

Parallel peptide production

03

Analyze

UPLC-UV / UPLC-MS

04

Characterize

Identity, purity & peptide content

05

Learn

Screening / SAR / hit-to-lead

QUALITY & ANALYTICAL SUPPORT

Confidence in Every Compound.

Every library member is supported by analytical characterization to provide confidence in compound quality and identity.

Peptide Content
MS-MS Sequencing
Water Content
UPLC-UV
UPLC-MS
Analytical UPLC-UV and Mass Spectrometry Characterization Interface

Have a Complex Peptide in Mind?

Let's discuss your molecule, synthesis requirements and library strategy.

Discuss Your Molecule
3D Molecular Peptide Structure Formulation